Udibaniso oluKhethekileyo lwesiza Faka ngokuchanekileyo imfuza ekujoliswe kuyo kwiNdawo eKhethekileyo eHotyiswe kuMfanekiso

Udibaniso lweSiza-Ngoluchanekileyo Faka iGene ekujoliswe kuyo kwiNdawo ethile eHotyo

Iinkcukacha zeMveliso

Iithegi zeMveliso

Ukudityaniswa kwendawo ethile yinkqubo yokwenza iwebhusayithi okanye isicelo silingane neemfuno ezizodwa zewebhusayithi okanye isicelo esithile.Yinkqubo ebandakanya ukwenza utshintsho kwikhowudi ekhoyo kunye nesakhiwo sewebhusayithi okanye isicelo ukwenzela ukuba isebenze ngakumbi kwaye isebenze kwiimfuno ezithile zesayithi.Ukudityaniswa kwendawo ethile kunokusetyenziselwa ukuguqula iimpawu ezikhoyo, ukongeza izinto ezintsha, kunye nokuphucula ukusetyenziswa ngokubanzi kwewebhusayithi okanye usetyenziso.Oku kuluncedo ngakumbi kumashishini aneewebhusayithi ezininzi okanye izicelo ezifuna ukudityaniswa ukuze zinike abathengi bawo amava angenamthungo.

I-AI-enabled Pro-antibody Design Platform

AlfaCap™

I-AI-enabled Site-Specific Integration I-Cell Line Development Platform

AlfaCell®

I-Al-enabled Cell Culture Media Development Platform

AlfaMedX®

Ukuhlanganiswa okuthe ngqo kwesiza kwiiseli ze-CHO yinkqubo esetyenziselwa ukwazisa i-gene yomdla kwindawo echazwe kakuhle kwi-genome ye-Chinese hamster ovary (CHO) iiseli.Le nkqubo ibandakanya ukusebenzisa i-site-specific recombinase enzyme ukujolisa ukulandelelana okuthe ngqo kwi-CHO cell genome kwaye emva koko idibanise imfuza yomdla ekulandeleni okujoliswe kuyo.Le ndlela ivumela ulawulo oluchanekileyo malunga nokufakwa kwezakhi zofuzo kwi-CHO cell genome kwaye inokunceda ukuphepha ukuhlanganiswa okungahleliwe, okunokuthi kube nemiphumo emibi kwiiseli.Iinzuzo eziphambili zale ndlela kukuba ibonelela ngolawulo olukhulu kunye nokuchaneka kwinkqubo yokudibanisa, kunye nezinga elikhulu lokuzinza kwe-gene ekuhambeni kwexesha.Ukongeza, le ndlela ingasetyenziselwa ukwazisa imfuza emininzi kwiindawo ezahlukeneyo ngaphakathi kweseli, iyenza ibe sisixhobo esinamandla sokuguqula imfuza.

Ukujolisa kwii-vectors

Ii-vectors ekujoliswe kuzo zisetyenziselwa ukudala izinto eziphilayo eziguqulwe ngokwemfuza ngokuzisa ulandelelwano oluthile lwe-DNA kwiigenomes zabo.Ngokuqhelekileyo zenziwe ngesiphawuli sofuzo esivumela ukuchongwa kweeseli ezilungisiweyo, isiphawuli esikhethiweyo esivumela ukukhethwa kweeseli ezilungisiweyo, kunye nommandla wokudibanisa i-homologous evumela ukudityaniswa kolandelelwano lwe-DNA olufunwayo kwigenome yento ephilayo ekujoliswe kuyo.Iivektha ezithagethayo zidla ngokusetyenziswa kungquzulwano lwemfuza, kugoqo lwemfuza, ukuhlelwa kofuzo, kunye nezinye iindlela zobunjineli bemfuzo.

Ngaphambili: CHO Umgca weSeli uBonelela ngeeNkonzo eziLungisiweyo

Okulandelayo: I-Cell Line ine-Advantages yoZinzo kunye neMveliso ePhakamileyo

Bhala umyalezo wakho apha kwaye uwuthumele kuthi